How To Write Nurse Resignation letter: Tips and Examples

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Crafting the Perfect Resignation Letter as a Nurse: Tips & Samples

Need to write a resignation letter as a nurse? This guide is here to help. Discover why a professional resignation letter is essential, what elements to include, and how to structure it clearly. Whether you’re leaving for a new opportunity or other reasons, learn how to exit gracefully with a well-crafted resignation letter.

Key Takeaways

  • A professional letter of Resignation is essential for maintaining integrity and leaving a positive impression on employers and colleagues, contributing to future opportunities.
  • Key elements of a letter of Resignation include a clear statement of intent, last working day, expressions of gratitude, and a commitment to assist with the transition process. Providing two weeks’ notice is the industry standard for resigning nurses.
  • Maintaining professionalism during the resignation process is vital, including notifying the employer in person, keeping communication clear, and preserving relationships post-resignation.

Why a Professional letter of Resignation is Important

Resigning from a nursing position involves more than simply informing your employer; it requires maintaining your professional integrity. A resignation letter serves as a formal acknowledgment of your intent to leave, which is a professional standard in nursing. Crafting such a letter reflects integrity, maturity, and gratitude, showcasing professionalism.

A well-crafted resignation letter can enhance your professional integrity and open doors for future opportunities. Employers and colleagues will remember your manner of departure, and a professional farewell can leave a lasting positive impression. Submitting a resignation letter with notice helps maintain relationships and ensures a smooth transition.

Expressing gratitude in your letter of Resignation by acknowledging the experiences and relationships developed in your position is key. A professional letter of Resignation ultimately protects your reputation and keeps future opportunities open. Negative language should be avoided in a letter of Resignation as it becomes part of your employee record and can affect your professional reputation.

Essential Elements of a Nurse Resignation Letter

A nurse resignation letter rests on a table alongside a stethoscope and a cup of coffee, symbolizing the transition process as the nurse prepares to leave their current position in the healthcare facility. The letter, written with a professional tone, expresses gratitude for the nursing career and outlines the intention to resign with ample notice.

A comprehensive nurse resignation letter should include several key elements. Clearly state your intent to resign, mentioning your position and your last working day to eliminate any ambiguity about your departure.

To leave a positive impression during your employment transition:

  • Express genuine gratitude for the opportunities and experiences you’ve had. This reflects well on your professionalism.
  • Offer to assist with the transition process, such as training new staff or handing off responsibilities.
  • Show your commitment to a smooth transition for your team and patients.

Include the notice period and, if appropriate, a reason for leaving. This transparency helps your employer understand your decision and make necessary arrangements. Most resignation letters should include the last working day, which is typically two weeks from the date of the letter. A well-rounded nurse resignation letter that includes these elements sets the stage for a respectful and professional departure.

How to Structure Your Nurse Resignation Letter

Properly structuring your nurse resignation letter is essential for clear and professional communication. Keep it short and straightforward, ensuring key information is presented clearly, concisely, and kindly. It’s important to proofread the nurse resignation letter carefully before submitting it to ensure professionalism.

Use a traditional greeting like ‘Dear [Supervisor’s Name]’ for a personal touch. The letter should include:

  • A header
  • A salutation
  • A statement of resignation
  • The last working day
  • A closing

This ensures all critical information is communicated effectively.

In the body, include a clear statement of your intent to resign and your last working day. Express gratitude for the opportunities you’ve had and your commitment to assisting with the transition. Close the letter with a polite statement and your signature. This structured approach ensures professionalism and respect.

Tips for Writing a Clear and Positive Nurse Resignation Letter

Maintaining a professional and positive tone is paramount when writing a letter of Resignation for nurse. Keep in mind the following guidelines:

  • Keep reasons for resigning positive.
  • Avoid verbosity and overly sentimental or robotic tones.
  • Use plain language that is simple yet elegant for clarity.

Guidelines for writing a resignation letter:

  • Express gratitude.
  • Avoid lengthy explanations to maintain tact.
  • Keep the letter short and simple, ideally under one page.
  • Format it correctly, using single spacing and standard margins for readability.
  • Proofread to ensure credibility and clarity.

A polite closing statement followed by your signature adds a respectful conclusion. Offering to assist with the transition shows professionalism and goodwill. These tips ensure that your resignation letter is clear, positive, and professional, leaving a lasting good impression.

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Sample Nurse Resignation Letter

Here is a sample resignation letter to help illustrate the points discussed.

Regina Rodriguez 123 Maple Street Anytown, USA May 21, 2025

Dear [Supervisor’s Name],

I am writing to formally resign from my nursing position at Maplewood Healthcare Facility Name, effective September 1, 2025. This decision has been difficult, but I have accepted a part-time nursing job closer to home to accommodate my family commitments. As a result, I will be joining a team of nurses at my new role, which will also support my nursing career.

I want to express my deepest gratitude for the opportunities and experiences I have had at Maplewood. Your support and guidance have been invaluable, and I have cherished my time working with such an exceptional team.

I am committed to ensuring a smooth transition and am willing to assist in training my replacement or completing necessary documentation related to my current employer and current role to the best of my ability during my notice period for my new job, as requested by my former manager.

Sincerely,

Regina Rodriguez

This sample resignation letter is good because it is clear, professional, and respectful. It states the resignation and effective date directly, gives a brief and valid reason without oversharing, expresses genuine gratitude, and offers help with the transition. The polite tone and structured format make it a graceful and positive way to resign.

Sample Registered Nurse Resignation Letter

Emily Carter
45 Oakwood Lane
Boston, MA 02115
June 5, 2025

Dear [Nurse Manager’s Name],

I am writing to formally resign from my position as a Registered Nurse at Boston General Hospital, effective July 1, 2025. After much consideration, I have decided to pursue a new opportunity that will allow me to grow professionally while balancing my family responsibilities.

I want to sincerely thank you and the entire team for the support, mentorship, and camaraderie I have experienced during my time here. It has been an honor to provide patient care alongside such skilled and compassionate colleagues.

I am committed to ensuring a smooth transition and will gladly assist with patient handovers, orientation for my replacement, and any other needs during my notice period.

Sincerely,
Emily Carter

Why this resignation letter is good

  • Professional yet warm tone – balances formality with gratitude, which is expected in U.S./Canada workplaces.
  • Clear statement of resignation – mentions role, hospital, and effective date upfront (reduces ambiguity).
  • Brief reason for leaving – framed positively (career growth + family balance) without negativity.
  • Gratitude expressed – acknowledges team and manager, strengthening professional relationships.
  • Transition support offered – shows responsibility and professionalism, key in healthcare settings.

Sample Head Nurse Resignation Letter

Michael Anderson
278 Willow Creek Drive
Toronto, ON M4B 1B3
July 12, 2025

Dear [Director of Nursing’s Name],

Please accept this letter as my formal resignation from my position as Head Nurse at St. Mary’s Medical Center, effective August 15, 2025. After careful thought, I have decided to transition into a leadership role outside of direct patient care that aligns with my long-term career goals.

I am truly grateful for the trust you placed in me to oversee and guide our nursing team. Leading such a talented group of professionals has been one of the most rewarding experiences of my career. I have learned invaluable lessons about leadership, teamwork, and patient-centered care.

To ensure a smooth transition, I will work diligently to update all staff schedules, complete pending administrative reports, and assist in onboarding whoever you appoint as interim or permanent replacement. I want to leave the unit in strong standing for both the staff and the patients we serve.

Sincerely,
Michael Anderson

Why this resignation letter is good

  • Leadership-focused – emphasizes managing and guiding a nursing team, not just patient care.
  • Professional reasoning – cites career progression while keeping it positive.
  • Acknowledges responsibility – mentions schedules, reports, and leadership duties (key tasks for a head/charge nurse).
  • Gratitude and respect – thanks management for trust and highlights growth.
  • Transition commitment – shows dedication to continuity for staff and patients.

Sample Resignation Letter For ICU Nurse

Sarah Mitchell
892 Pine Ridge Avenue
Chicago, IL 60611
August 3, 2025

Dear [ICU Supervisor’s Name],

I am writing to formally resign from my position as ICU Nurse at Chicago Mercy Hospital, effective September 1, 2025. After much reflection, I have chosen to relocate to be closer to my family and pursue a nursing role in another healthcare facility.

Working in the Intensive Care Unit has been one of the most challenging and rewarding experiences of my career. I am deeply grateful for the opportunity to care for critically ill patients and for the support I have received from the entire ICU team.

To ensure continuity of patient care, I will work closely with you and my colleagues to complete all charting, assist with patient handovers, and support orientation for new staff members during my notice period.

Sincerely,
Sarah Mitchell

Why this resignation letter is good

  • Direct and clear – clearly states position, hospital, and effective resignation date.
  • Acknowledges the intensity of ICU work – highlights both the challenges and rewards, making it relatable to ICU nurses.
  • Personal but professional reason – relocation framed positively, avoids unnecessary detail.
  • Patient safety focus – explicitly mentions charting and patient handover, which is crucial in ICU settings.
  • Team acknowledgment – shows respect and appreciation for colleagues in a high-pressure environment.

Sample Resignation Letter For ER Nurse

Jessica Reynolds
410 Cedar Grove Lane
Dallas, TX 75219
September 6, 2025

Dear [Nurse Manager’s Name],

Please accept this letter as my formal resignation from my position as Emergency Room Nurse at Dallas City Medical Center, effective October 5, 2025. After much thought, I have decided to accept a position at another healthcare facility that will provide me with new challenges and opportunities for professional growth.

Working in the ER has been a deeply fulfilling part of my nursing journey. The fast-paced environment has taught me resilience, adaptability, and the importance of teamwork under pressure. I am grateful for the support and camaraderie I have experienced within this department.

I will ensure a smooth transition by completing all outstanding documentation, assisting with patient handovers, and offering support to colleagues during my remaining shifts.

Sincerely,
Jessica Reynolds

Why this resignation letter is good

  • Clear and concise – specifies role, department, hospital, and effective date.
  • Acknowledges unique ER experience – highlights fast-paced, high-pressure environment, which resonates with ER nurses.
  • Positive departure reason – frames the new opportunity as growth, not dissatisfaction.
  • Transition assurance – emphasizes completing documentation and patient handover, which are crucial in ER settings.
  • Gratitude – thanks the team, reinforcing professionalism and maintaining good relations.

Sample NICU Nurse Resignation Letter

Amanda Lewis
132 Willowbrook Drive
Seattle, WA 98109
October 2, 2025

Dear [NICU Supervisor’s Name],

I am writing to formally resign from my position as NICU Nurse at Seattle Children’s Hospital, effective November 1, 2025. After thoughtful consideration, I have decided to step into a role that will allow me to focus on continuing my education in neonatal care and further advance my nursing career.

Working in the NICU has been one of the most meaningful experiences of my life. Providing specialized care to newborns and supporting their families during difficult times has shaped me both personally and professionally. I will always be grateful for the trust you placed in me and for the opportunity to work alongside such a dedicated team.

During my notice period, I will ensure a seamless transition by completing patient documentation, assisting with care plans, and supporting orientation for staff members who will continue providing excellent care in the unit.

Sincerely,
Amanda Lewis

Why this resignation letter is good

  • Role-specific acknowledgment – emphasizes neonatal care and family support, unique to NICU nurses.
  • Clear resignation details – specifies position, hospital, and final working date upfront.
  • Positive and professional reason – frames resignation around education and career advancement.
  • Gratitude and empathy – thanks team and acknowledges the emotional depth of NICU work.
  • Commitment to transition – highlights care continuity and patient documentation, critical in neonatal settings.

Sample Resignation Letter For Surgical Nurse

Daniel Foster
589 Evergreen Street
Vancouver, BC V6H 1A5
November 10, 2025

Dear [Operating Room Supervisor’s Name],

Please accept this letter as my formal resignation from my position as Operating Room Nurse at Vancouver General Hospital, effective December 15, 2025. I have recently accepted a position at another medical facility that will allow me to broaden my experience in perioperative care.

Working in the operating room has been an incredibly rewarding experience. Assisting surgeons and supporting patients through critical procedures has given me invaluable professional growth. I am deeply grateful for the trust and collaboration of the surgical team and nursing staff.

To ensure a smooth transition, I will finalize all surgical case documentation, assist in preparing the OR schedule, and provide support to colleagues during my remaining shifts.

Sincerely,
Daniel Foster

Why this resignation letter is good

  • Role-specific detail – highlights surgical case support and perioperative care, central to OR nurses.
  • Clarity – states position, hospital, and final working day upfront.
  • Positive reason – frames resignation around professional growth and new opportunities.
  • Acknowledges teamwork – thanks surgeons and staff, reinforcing collaborative spirit.
  • Transition assurance – addresses surgical documentation and OR scheduling, showing responsibility.

Sample Resignation Letter For Certified Nursing Assistant (CNA)

Laura Bennett
76 Maplewood Court
Cleveland, OH 44115
December 1, 2025

Dear [Supervisor’s Name],

I am writing to formally resign from my position as Nursing Assistant at Cleveland Regional Hospital, effective December 30, 2025. I have accepted another opportunity that will allow me to continue developing my skills while staying closer to my family.

I am thankful for the experience I’ve gained working alongside the nursing team and caring for patients. The support and guidance I have received have helped me grow both personally and professionally.

I will do my best to make this transition smooth by finishing all assigned tasks and assisting with patient care responsibilities until my final day.

Sincerely,
Laura Bennett

Why this resignation letter is good

  • Simple and clear – matches the supportive, entry-to-mid-level role of a CNA.
  • Direct resignation details – specifies role, facility, and end date without over-explaining.
  • Positive but modest tone – thanks team for guidance, appropriate for junior/support staff.
  • Transition assurance – commits to completing tasks and helping until the last day, showing reliability.
  • Keeps it short – concise style works well for non-supervisory nursing roles.

Sending Your Resignation Letter: Best Practices

A person sending a resignation letter via email, with a blurred screen.

Before submitting your resignation letter, consider notifying your employer in person. This shows respect and allows for an open discussion about your departure. It is advisable for nurses to have a conversation with their manager before submitting their resignation letter.

If sending your resignation letter via email, consider the following:

  • Include an informative subject line that highlights your intention to resign. An example could be “Resignation – John Doe.”
  • This clarity ensures your message is received and understood promptly.
  • Electronically save a copy for your records.

Avoid discussing your resignation with colleagues before informing your direct supervisor to maintain professionalism. Providing as much notice as possible, at least two weeks’ notice, is standard practice to facilitate a smooth transition.

Handling Immediate Resignations

Sometimes, immediate resignations are unavoidable due to emergencies such as family illness or relocation. In such cases, submit your resignation letter quickly while maintaining professionalism.

Quick-use templates for resignation letters allow for swift submission without losing professionalism. However, adding a human resources touch to these templates is important to avoid feeling generic. Utilizing templates can simplify the process of writing a resignation letter for nurses.

Relocation or urgent medical situations may require a quick resignation letter submission. Even in these scenarios, include essential elements and express your commitment to a smooth transition.

Transitioning Responsibilities

Transitioning responsibilities smoothly is vital for maintaining continuity of care and operations within a healthcare facility. In your resignation letter, express your commitment to assisting with the transition process. Offer to help with the handover of duties, such as training replacements or completing necessary documentation. Offering to assist with the transition, such as training a replacement, demonstrates professionalism. This gesture reinforces a collaborative work environment and demonstrates your dedication to your team’s success.

Including a transition assistance offer in your resignation letter can facilitate a smoother handover of responsibilities. This eases the burden on colleagues and leaves a positive impression on your current organization.

Maintaining Professional Relationships Post-Resignation

A nurse maintaining professional relationships post-resignation with colleagues, with faces blurred.

Maintaining professional relationships post-resignation is crucial for career growth and professional development. Writing a positive resignation letter helps preserve relationships with supervisors and organizations.

To maintain goodwill and preserve professional relationships during your resignation:

  • Convey deep appreciation for the support and friendship from colleagues.
  • Offer assistance during the transition period.
  • Include your contact information in your resignation letter to facilitate future communication.

Expressing gratitude towards the team and indicating the value of professional growth relationships helps ensure you leave on good terms and maintains the possibility of future opportunities.

Summary

In summary, writing a professional resignation letter is a crucial step in leaving your nursing job gracefully. A well-structured letter that includes clear intent, gratitude, and an offer to assist with the transition reflects your professionalism and helps maintain positive relationships. By following the tips and best practices outlined in this guide, you can ensure a smooth transition and leave your current role on a positive note.

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  • Regina is a seasoned career content writer specializing in resume writing, job search strategies, and professional development. With over 7 years of experience crafting impactful career advice, Regina has helped thousands of job seekers—from recent graduates to senior executives—present their skills and achievements in a compelling way that stands out to recruiters.

    Her work combines deep industry knowledge with practical insights, drawn from collaborating closely with certified career coaches, HR professionals, and hir…

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